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CNS Depressants / Medication

Alprazolam

Identity, uses and research, side effects, dosage context, pricing and online access.

MedicationCNS DepressantsSchedule IV
Reference nameAlprazolam
Entry typeMedication
CategoryCNS Depressants
Drug familyBenzodiazepine
Brand contextXanax and Xanax XR
Formulation contextImmediate-release alprazolam; Extended-release alprazolam

DrugRX editorial reference · Sources consulted · Not independently medically reviewed

Alprazolam 0.4 mg tablets from Japan. Appearance varies by manufacturer and market.

Alprazolam 0.4 mg tablets from Japan. Appearance varies by manufacturer and market.

HmanJp · Public domain

About Alprazolam

Alprazolam is a benzodiazepine sold in products including Xanax and extended-release Xanax XR.

Also searched as: Xanax · Xanax XR

PRODUCT FORMULATIONS

Available strengths

Strength is the amount in a tablet, capsule, liquid or patch. Different formulations are listed separately.

Product & formulationStrengths
Xanax / alprazolam
Immediate-release oral tablet
0.25 mg · 0.5 mg · 1 mg · 2 mgProduct label · Checked 2026-10-31

Dosages in the product label

Xanax immediate release — Generalized anxiety disorder

Population: Adults

Initial: 0.25–0.5 mg three times daily. Maximum recommended: 4 mg/day in divided doses.

Older adults and people with hepatic impairment use lower starting doses. Panic-disorder and XR instructions differ.

Prescribing information · Checked 2026-10-31

PRICE, COST & AVAILABILITY

Buy Alprazolam: pricing & legal access

Alprazolam online: availability & product information

Saved U.S. price estimates from Drugs.com for the exact products and quantities below. These are dated estimates, not live pharmacy quotes or insurance copays. Discounts and local availability vary.

Product / strengthQuantityPrice (USD)
Generic alprazolam
0.5 mg
Immediate-release oral tablet
30 tablets$8.45
Drugs.com published cash estimate
Drugs.com price guide
Checked 2026-10-31
Generic alprazolam
2 mg
Immediate-release oral tablet
30 tablets$10.83
Drugs.com published cash estimate
Drugs.com price guide
Checked 2026-10-31
Generic alprazolam
0.5 mg
Extended-release oral tablet
60 tablets$23.01
Drugs.com published cash estimate
Drugs.com price guide
Checked 2026-10-31

Prices refer to medication only; consultation, administration and monitoring costs may be additional. Prescription products require a valid prescription and a licensed pharmacy. Check the exact formulation before comparing offers.

DETAILED REFERENCE

Alprazolam information

Uses and formulations

Used for anxiety and panic disorders. Immediate-release and extended-release tablets have different directions.

Sources: MedlinePlus — Alprazolam

Side effects and serious risks

Drowsiness, dizziness and impaired coordination can occur. Dependence and potentially severe withdrawal can develop.

Sources: MedlinePlus — Alprazolam

Dosage and directions

Use the prescribed dose and duration. Do not stop abruptly; a clinician may need to reduce treatment gradually.

Sources: MedlinePlus — Alprazolam

Interactions and precautions

Combining alprazolam with opioids or alcohol can cause life-threatening sedation and breathing problems. Review all sleep and anxiety medicines.

Sources: MedlinePlus — Alprazolam

Pharmacology and mechanism

Alprazolam enhances inhibitory GABA signaling through benzodiazepine-sensitive GABA-A receptors. Sedation and impaired coordination can accompany its anti-anxiety effects.

Sources: DailyMed — Xanax prescribing information

Formulations and product identification

The active ingredient alone does not describe a finished product. These distinctions matter when reading a label or comparing prescriptions.

Product or formulationImportant distinction
Immediate-release alprazolamDifferent release characteristics from XR.
Extended-release alprazolamRequires formulation-specific administration.

Sources: DailyMed — Xanax prescribing information

Monitoring and treatment follow-up

Follow-up considers anxiety or panic symptoms, sedation, memory and coordination. Alprazolam is affected by CYP3A interactions, so adding or stopping another medicine can change exposure.

Sources: DailyMed — Xanax prescribing information

Dependence and stopping treatment

Physical dependence can develop with regular use. Abrupt cessation or rapid reduction can cause serious withdrawal, including seizures. Withdrawal symptoms can resemble returning anxiety but may require a different clinical response.

Sources: DailyMed — Xanax prescribing information

How it differs from related medicines

Xanax is a brand, while alprazolam is the active ingredient. An extended-release tablet is not simply another shape of the immediate-release product. A pill’s appearance or a seller’s Xanax label cannot verify authenticity.

Sources: DailyMed — Xanax prescribing information

Sources and editorial notes

Prepared by DrugRX using the references linked below. Sources were consulted on 2026-10-31. This page has not been independently reviewed by a clinician. Research findings, medication approval and legal permission are separate questions.

  1. MedlinePlus — Alprazolam
  2. DEA — Controlled substances alphabetical list (October 2026)
  3. DailyMed — Xanax prescribing information
  4. Drugs.com — alprazolam price guide

Legal information is a dated U.S. reference. Product rules and local laws may change. Where the evidence does not establish a dose, interaction profile or price, the page states that limitation.