Buprenorphine/naloxone combination tablet (Roxane Laboratories), not buprenorphine alone.
Tmeers91 · CC BY-SA 3.0
About Buprenorphine
Buprenorphine is a partial opioid agonist used in different products for opioid use disorder or pain.
Also searched as: Bupe · Suboxone · Subutex · Sublocade · Buprenex
Available strengths
Strength is the amount in a tablet, capsule, liquid or patch. Different formulations are listed separately.
| Product & formulation | Strengths |
|---|---|
| Suboxone (buprenorphine/naloxone) Sublingual or buccal film | 2 mg / 0.5 mg · 4 mg / 1 mg · 8 mg / 2 mg · 12 mg / 3 mg First number is buprenorphine; second is naloxone. Other buprenorphine products are not interchangeable by these numbers. Product label · Checked 2026-10-31 |
Dosages in the product label
Suboxone buprenorphine/naloxone film — Opioid use disorder maintenance
Population: Patients already in clinician-supervised maintenance
Typical labeled target: 16 mg / 4 mg once daily; individualized maintenance range: 4 mg / 1 mg to 24 mg / 6 mg daily.
First amount is buprenorphine, second naloxone. This is maintenance information, not an induction or self-detox protocol.
Prescribing information · Checked 2026-10-31
Buy Buprenorphine: pricing & legal access
Buprenorphine online: availability & product information
Saved U.S. price estimates from Drugs.com for the exact products and quantities below. These are dated estimates, not live pharmacy quotes or insurance copays. Discounts and local availability vary.
| Product / strength | Quantity | Price (USD) |
|---|---|---|
| Generic buprenorphine (without naloxone) 2 mg Sublingual tablet | 30 tablets | $18.65–$19.56 Drugs.com published cash estimate Drugs.com price guide Checked 2026-10-31 |
Prices refer to medication only; consultation, administration and monitoring costs may be additional. Prescription products require a valid prescription and a licensed pharmacy. Check the exact formulation before comparing offers.
Buprenorphine information
Uses and formulations
Buprenorphine/naloxone films and tablets are used in opioid use disorder care. Pain products and long-acting injections have separate indications and instructions.
Side effects and serious risks
Constipation, headache and nausea can occur. Sedation and respiratory depression remain possible. Incorrect treatment initiation may precipitate withdrawal.
Dosage and directions
Starting, changing or stopping treatment requires product-specific clinical guidance. Films, tablets, injections and patches are not directly interchangeable.
Interactions and precautions
Discuss alcohol, benzodiazepines and other sedatives with the clinician. Do not stop effective treatment on your own because an interaction is suspected.
U.S. federal classification
Listed federally in Schedule III. Classification does not by itself establish that a particular product is approved or that an online transaction is lawful. State requirements and product-specific rules also apply.
Sources: DEA — Controlled substances alphabetical list (October 2026)
Pharmacology and mechanism
Buprenorphine is a partial agonist at mu-opioid receptors. In opioid use disorder treatment it helps suppress withdrawal and craving. Naloxone is an additional ingredient in certain products, not a synonym for buprenorphine.
Formulations and product identification
The active ingredient alone does not describe a finished product. These distinctions matter when reading a label or comparing prescriptions.
| Product or formulation | Important distinction |
|---|---|
| Buprenorphine/naloxone film | A combination product used in opioid use disorder care. |
| Other buprenorphine formulations | Pain products and long-acting preparations have separate instructions. |
Monitoring and treatment follow-up
Follow-up evaluates withdrawal control, cravings, sedation, other substance exposure and practical treatment needs. Dental problems have been reported with products dissolved in the mouth; product-specific oral care instructions matter.
Dependence and stopping treatment
Physical dependence can occur during effective treatment. That does not mean treatment has failed. Starting too soon after certain other opioids can precipitate withdrawal; stopping ongoing care or changing formulations should be clinically planned.
How it differs from related medicines
Suboxone combines buprenorphine with naloxone. A buprenorphine pain patch or injection is not a substitute chosen by matching milligram amounts. Eligibility, absorption and treatment goals differ across formulations.
Sources and editorial notes
Prepared by DrugRX using the references linked below. Sources were consulted on 2026-10-31. This page has not been independently reviewed by a clinician. Research findings, medication approval and legal permission are separate questions.
- MedlinePlus — Buprenorphine and naloxone
- DEA — Controlled substances alphabetical list (October 2026)
- DailyMed — Suboxone film prescribing information
- Drugs.com — buprenorphine price guide
Legal information is a dated U.S. reference. Product rules and local laws may change. Where the evidence does not establish a dose, interaction profile or price, the page states that limitation.