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Other Prescription Medications / Medication

Pregabalin

Identity, uses and research, side effects, dosage context, pricing and online access.

MedicationOther Prescription MedicationsSchedule V
Reference namePregabalin
Entry typeMedication
CategoryOther Prescription Medications
Drug familyGabapentinoid anticonvulsant
Brand contextLyrica and Lyrica CR
Formulation contextCapsules or oral solution; Extended-release tablets

DrugRX editorial reference · Sources consulted · Not independently medically reviewed

Lyrica (pregabalin) 150 mg packaging in Finland.

Lyrica (pregabalin) 150 mg packaging in Finland.

Acdx · CC BY-SA 3.0

About Pregabalin

Pregabalin, known as Lyrica, is a gabapentinoid used for several nerve-pain and seizure-related conditions.

Also searched as: Lyrica

PRODUCT FORMULATIONS

Available strengths

Strength is the amount in a tablet, capsule, liquid or patch. Different formulations are listed separately.

Product & formulationStrengths
Lyrica / pregabalin
Oral capsule
25 mg · 50 mg · 75 mg · 100 mg · 150 mg · 200 mg · 225 mg · 300 mgProduct label · Checked 2026-10-31
PRICE, COST & AVAILABILITY

Buy Pregabalin: pricing & legal access

Pregabalin online: availability & product information

Saved U.S. price estimates from Drugs.com for the exact products and quantities below. These are dated estimates, not live pharmacy quotes or insurance copays. Discounts and local availability vary.

Product / strengthQuantityPrice (USD)
Generic pregabalin
100 mg
Oral capsule
30 capsules$5.45–$9.87
Drugs.com published cash estimate
Drugs.com price guide
Checked 2026-10-31

Prices refer to medication only; consultation, administration and monitoring costs may be additional. Prescription products require a valid prescription and a licensed pharmacy. Check the exact formulation before comparing offers.

DETAILED REFERENCE

Pregabalin information

Uses and formulations

Indications include certain neuropathic pain conditions, fibromyalgia and adjunctive treatment of partial seizures. Extended-release indications differ.

Sources: MedlinePlus — Pregabalin

Side effects and serious risks

Dizziness, sleepiness, swelling and weight gain can occur. Breathing difficulty or a serious allergic reaction needs urgent care.

Sources: MedlinePlus — Pregabalin

Dosage and directions

The prescription may depend on kidney function. Capsules and extended-release tablets have different instructions; do not stop suddenly without advice.

Sources: MedlinePlus — Pregabalin

Interactions and precautions

Opioids and other sedatives can increase respiratory risk. Tell the prescriber about swelling, heart conditions and mood changes.

Sources: MedlinePlus — Pregabalin

Pharmacology and mechanism

Pregabalin binds to alpha-2-delta sites associated with voltage-gated calcium channels. It is used in specific pain and seizure contexts and is not an opioid analgesic.

Sources: DailyMed — Lyrica prescribing information

Formulations and product identification

The active ingredient alone does not describe a finished product. These distinctions matter when reading a label or comparing prescriptions.

Product or formulationImportant distinction
Capsules or oral solutionIndications differ from certain extended-release products.
Extended-release tabletsRequire their own food and administration instructions.

Sources: DailyMed — Lyrica prescribing information

Monitoring and treatment follow-up

Review kidney function, dizziness, edema, weight changes and daily functioning. Breathing risk increases with certain depressant medicines or underlying respiratory problems; new breathing difficulty needs prompt assessment.

Sources: DailyMed — Lyrica prescribing information

Dependence and stopping treatment

Physical dependence and withdrawal symptoms can occur. Abrupt cessation is not a routine way to assess whether treatment is still needed. A reduction plan considers the indication, seizure history and treatment duration.

Sources: DailyMed — Lyrica prescribing information

How it differs from related medicines

Lyrica CR is not simply a differently shaped capsule. Pregabalin also differs from gabapentin in its pharmacokinetics and dosing. The two medicines cannot be substituted by matching their milligram strengths.

Sources: DailyMed — Lyrica prescribing information

Sources and editorial notes

Prepared by DrugRX using the references linked below. Sources were consulted on 2026-10-31. This page has not been independently reviewed by a clinician. Research findings, medication approval and legal permission are separate questions.

  1. MedlinePlus — Pregabalin
  2. DEA — Controlled substances alphabetical list (October 2026)
  3. DailyMed — Lyrica prescribing information
  4. Drugs.com — pregabalin price guide

Legal information is a dated U.S. reference. Product rules and local laws may change. Where the evidence does not establish a dose, interaction profile or price, the page states that limitation.