Teva bupropion 150 mg product, as identified by the photographer.
Avopasia · CC BY-SA 4.0
About Bupropion
Bupropion is an antidepressant also used in a separate treatment context to help people stop smoking.
Also searched as: Wellbutrin · Zyban
Available strengths
Strength is the amount in a tablet, capsule, liquid or patch. Different formulations are listed separately.
| Product & formulation | Strengths |
|---|---|
| Wellbutrin XL / bupropion 24-hour extended-release oral tablet | 150 mg · 300 mg Immediate-release and SR products have different dosing schedules. Product label · Checked 2026-10-31 |
Dosages in the product label
Wellbutrin XL — Major depressive disorder
Population: Adults
Initial: 150 mg once each morning. Usual target: 300 mg once daily.
Do not apply this schedule to SR or immediate-release products. Seizure risk and kidney/liver impairment affect prescribing.
Prescribing information · Checked 2026-10-31
Buy Bupropion: pricing & legal access
Bupropion online: availability & product information
Saved U.S. price estimates from Drugs.com for the exact products and quantities below. These are dated estimates, not live pharmacy quotes or insurance copays. Discounts and local availability vary.
| Product / strength | Quantity | Price (USD) |
|---|---|---|
| Generic bupropion XL 150 mg 24-hour extended-release oral tablet | 30 tablets | $10.58–$14.40 Drugs.com published cash estimate Drugs.com price guide Checked 2026-10-31 |
| Generic bupropion XL 300 mg 24-hour extended-release oral tablet | 30 tablets | $11.86–$13.93 Drugs.com published cash estimate Drugs.com price guide Checked 2026-10-31 |
Prices refer to medication only; consultation, administration and monitoring costs may be additional. Prescription products require a valid prescription and a licensed pharmacy. Check the exact formulation before comparing offers.
Bupropion information
Uses and formulations
Wellbutrin and Zyban are familiar names. Immediate-, sustained- and extended-release products have different directions.
Sources: MedlinePlus — Bupropion
Side effects and serious risks
Dry mouth, insomnia and nausea can occur. Seizures and changes in mood or suicidal thinking are serious risks.
Sources: MedlinePlus — Bupropion
Dosage and directions
Use only the prescribed release formulation. Do not crush sustained- or extended-release tablets or combine different bupropion products independently.
Sources: MedlinePlus — Bupropion
Interactions and precautions
Seizure or eating-disorder history and abrupt alcohol or sedative withdrawal need review. MAO inhibitors and other medicines may interact.
Sources: MedlinePlus — Bupropion
Pharmacology and mechanism
Bupropion has noradrenergic and dopaminergic effects, although its full antidepressant mechanism is not established. It is not an SSRI and has a different interaction and adverse-effect profile.
Formulations and product identification
The active ingredient alone does not describe a finished product. These distinctions matter when reading a label or comparing prescriptions.
| Product or formulation | Important distinction |
|---|---|
| Immediate-release bupropion | Has its own dosing schedule. |
| SR and XL products | Different release designs; not identical directions. |
| Smoking-cessation products | The treatment indication must be identified. |
Monitoring and treatment follow-up
Clinical review includes mood, sleep and blood pressure. Seizure risk is an important consideration, especially with particular medical histories or other medicines that lower the seizure threshold.
Dependence and stopping treatment
Using more than one bupropion-containing product can unintentionally increase exposure. A brand prescribed for depression and another prescribed for smoking cessation should not be combined independently.
How it differs from related medicines
Wellbutrin XL and bupropion SR differ in release characteristics. Bupropion is also different from prescription amphetamine stimulants, even though both may have activating effects. A shared subjective effect is not evidence of interchangeability.
Sources and editorial notes
Prepared by DrugRX using the references linked below. Sources were consulted on 2026-10-31. This page has not been independently reviewed by a clinician. Research findings, medication approval and legal permission are separate questions.
- MedlinePlus — Bupropion
- DailyMed — Wellbutrin XL prescribing information
- Drugs.com — bupropion price guide
Legal information is a dated U.S. reference. Product rules and local laws may change. Where the evidence does not establish a dose, interaction profile or price, the page states that limitation.