LSD (lysergic acid diethylamide)

LSD can profoundly change perception, mood and the sense of time. A name, blotter design or seller description cannot identify the active substance or its quantity.

Sources: DEA — LSD

Anxiety, panic, increased heart rate and blood pressure, sweating and sleeplessness may occur. Persistent perceptual disturbances have also been reported.

Sources: DEA — LSD

This page provides no self-use dose. Clinical research uses defined materials, screening and monitoring; that setting differs from an unknown blotter or liquid.

Sources: FDA — Psychedelic drugs: clinical investigations

Altered judgment creates injury risks. Psychiatric history and other psychoactive medicines are relevant to clinical screening. New severe confusion, seizures or chest pain warrants urgent assessment.

Sources: NIH — Psychedelic and dissociative drugs

LSD has serotonergic psychedelic activity. Changes can involve visual perception, thought, emotion and the sense of time. A description such as acid refers to a common name, not an analytical confirmation of a product.

Sources: DEA — LSD

Acute perceptual changes and later recurring perceptual symptoms are different issues. A person’s apparent recovery from intoxication does not establish whether persistent symptoms need evaluation. Reported experiences also vary with circumstances and other substances.

Sources: DEA — LSD

Paper artwork, color or liquid packaging cannot distinguish LSD from another chemical. Some other hallucinogens have been sold as LSD, including NBOMe compounds with different toxicity concerns.

Sources: DEA — 25I-, 25C- and 25B-NBOMe

A small human report supports conversion of 1P-LSD to LSD. That metabolic finding does not erase the identity of the starting compound or prove identical quality, legal treatment or safety for products bearing either name.

Sources: 1P-LSD pharmacokinetics in two volunteers (2020)